Nishishu was born in Bunsei 12 (1829) to the family of a physician in the Tsuwano Domain, a philosopher who first introduced Western philosophy to our country. Inspired by Perry's visit, he studied abroad in the Netherlands and studied law and Western philosophy. After his return to Japan, he served as a political advisor to the 15th general, Gyeonghee, and after the restoration, he served as a bureaucrat in the Army, the Ministry of Education, and the Ministry of Internal Affairs. He was active in many fields, including being involved in drafting the Meiji Constitution under Aruto, Yamagata Prefecture. Mori Ogai's Mori family is a relative, and his house is close. The former residence stands opposite the old house of Ogai, across the Tsuwano River. Both the thatched main building, which was rebuilt in the first year of Ansei (1854), and the Tozo, which had Zhou's study room, were designated as historic sites.